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source: Ethical Consumer Magazine 54 Aug/Sept 98


Animal Testing Laboratories

One of the biggest contract testing laboratories, Huntingdon Life Sciences has received heavy coverage both in the national press and in EC. However, it is not alone in conducting animal testing. This article looks at four of the other largest contract testing laboratories in the UK.

During 1997, in the UK approximately 2.64 million experiments were carried out on animals.17 These experiments involved mice, rats and other rodents, birds, fish, rabbits, dogs, cats and non-human primates. Although the testing of finished cosmetic products has since been banned, this only represented 10% of cosmetic tests carried out and 0.1% of the total animals used for scientific procedures. The majority of tests were carried out by commercial companies, while the rest were by universities, charities, government departments and other public bodies.

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According to Pat Rattigan from British Anti Vivisection Association (BAVA) there are over 350 licensed laboratories across the UK.4 Unfortunately, it is not possible to find out exactly where tests are carried out. Although the Home Office does hold these details, a spokesperson told us that this information is confidential, partly because pharmaceutical companies and contract houses want their ideas protected, and partly because of security fears that this information could get into the ‘wrong hands’ and be ‘misused’.1 A number of animal rights organisations confirmed the secrecy of the testing industry and Naturewatch argue that "it is this very secrecy which prevents progress in reducing and stopping the use of animals for experimental purposes".

Despite this secrecy, it has been possible to discover who some of the largest contract testing laboratories in the UK are. According to BUAV, BAVA and the Animal Rights Coalition, five of the largest contract laboratories are Huntingdon Life Sciences, Covance Laboratories, Quintiles Toxicology Pathology Services, BIBRA and Inveresk Research International.

These laboratories conduct testing on behalf of pharmaceutical, agrochemical and household product companies and are quite likely to be conducting tests for overseas companies as well. According to Sarah Kite from BUAV, the most common type of tests conducted at these laboratories are toxicity tests such as the Lethal Dose Test (LD50), where animals are force-fed a substance to find out at which dose half of them die. Although this test is in decline, fixed dose procedures still involve the pain and death of large numbers of animals.


Quintiles Toxicology Pathology Services

Quintiles Toxicology Pathology Services is based in Ledbury in Herefordshire and is part of the US owned Quintiles Transnational Corporation, which describes itself as "the largest contract research organisation in the world". It has more than 80 offices in 28 countries, and employs over 13,000 people world-wide. According to Tony Peters from the campaign group ‘Stop Quintiles Animal Tests’ (SQAT), the Ledbury site conducts tests for a number of commercial organisations and uses mice, rats, rabbits, guinea pigs and beagles. Products tested include drugs, cosmetics, household products, surgical implants, household cleaners and agrochemicals. This information, like most of the information gained by campaign groups has been gathered from workers and ex-workers. SQAT’s campaign has concentrated on regular pickets outside the laboratory with periodic larger demonstrations. So far, campaigners claim some successes, with a number of workers leaving employment at the laboratory as a result of the pickets.

Quintiles has a number of sites in the UK, however Ledbury is the only one where animal tests are carried out. Because of this, Tony Peters is optimistic that the company can be persuaded to withdraw its investment in animal experimentation.

To find out how to add your support to the campaign, dates of demonstrations and pickets, contact: Stop Quintiles’ Animal Tests (SQAT), P.O. Box 127, Kidderminster, Worcs DY10 3UZ. Phone Louise on 01562 745 778.

l Quintiles Toxicology Pathology Services, Bromyard Road, Ledbury, Herefordshire HR8 1LH      -Tel: 01531 634121
l Quintiles Transnational Corporation, PO Box 13979, Research Triangle Park, NC 27709, USA.


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Covance Laboratories

Formerly known as Hazleton, the Covance laboratory in Harrogate is owned by Covance Laboratories Inc. in the US. Covance Laboratories Inc describes itself as "the world’s largest pre-clinical toxicology research organisation" (sounds familiar) and has facilities in the US and Germany as well as the Harrogate site.

According to its website, Covance Inc (the parent of Covance Laboratories Inc) "conducts more development studies in a year than any single pharmaceutical company" and employs over 6,000 people world-wide, operating in 17 countries. Its 1997 revenue amounted to $591 million and clients included "the top 50 global pharmaceutical companies". As well as offering testing, it also supplies and breeds animals, claiming to be the worlds largest breeder of dogs for experiments. Amongst the animals Covance Laboratories Inc. supply are its own breed of dog, the trademarked "Mini-Mongrelä" (the mind boggles), the registered Elite New Zealand WhiteÒ rabbit and the "MutaäMouse", as well as other purpose-bred canines, guinea pigs and non-human primates. Covance is also known to be involved in importing wild-caught primates. Its testing laboratory in Harrogate employees over 800 people and is also planning to expand having recently "received permission to build another toxicology lab on site". According to ARCNews, animals currently used in the laboratories include dogs, primates, rabbits, mice, rats and birds and there are thousands on site at any one time. An undercover investigator in the early 90s discovered that macaques used in a drug inhalation test were mistreated by technicians.

There is a campaign against Covance. You can contact them at:  PO Box 323, York.

l Covance Laboratory: Otley Road, Harrogate, North Yorkshire HG3 1PY. Tel: 01432 500011.
l US Headquarters: 210 Carnegie Center, Princeton, NJ 08540-6233.
l There is also a free address and phone number in the UK: Licence NO LS AC1, Covance Research Unit, Leeds, Freepost, LS2 9NG. Tel: 0800 591 570.  


Inveresk Research International

Inveresk Research (not to be confused with the paper company), based in Scotland is a member of the Swiss SGS Group (Societe Generale de Surveillance). It provides "animal and human volunteer data"12 and offers research in pharmaceuticals, agrochemicals, veterinary medicines, biopharmaceuticals, chemicals and consumer products. Services offered include acute toxicity, animal eye and skin irritation, animal skin sensitisation and chronic toxicity tests13 and animals have included rodents, dogs and primates. A BUAV research report published in July 1994 discovered that Inveresk was involved in using primates in pharmaceutical research. BUAV was particularly critical of a study involving six castrated cynomologus macaques which failed to point out the possibility of species difference. BUAV commented that the 1986 Animals (Scientific Procedures) Act was supposed to prevent studies such as this one.

The parent company, SGS is well known for its accreditation subsidiaries. They are accreditors for a social auditing scheme as well as environmental accreditation schemes such as the Forest Stewardship Council label.

l Corporate Headquarters: Inveresk Research International Ltd, Tranent EH33 2NE, Tel: 01875 614545

l SGS Generale de Surveillance Holding S.A, Rue des Alpes 8, CH-1211, Geneve 1, Switzerland.


BIBRA

BIBRA (British Industrial Biological Research Association) used to be the most prominent contract testing laboratory in the UK. Based in Surrey, its income is derived from member subscriptions and contract testing, mostly carried out for member companies. The last publicly available membership list dates back to 1994 and included over 100 companies such as Bristol-Myers Squibb, British Sugar plc and Mars Confectionery. During that year, BIBRA carried out 22,000 experiments on animals. A call to BIBRA’s information department discovered that member lists were no longer published for ‘security reasons’ and that information about the number of tests it carries out was only available from the Home Office, apparently unaware (or perhaps not) that the Home Office is ‘unable’ to release that information. According to BUAV, BIBRA has reduced the numbers of animals used, but has yet to abandon animal testing completely.

l BIBRA Toxicology International, Woodmonsterne Road, Carshalton, Surrey SM5 4DS. Tel: 0181 652 1000.



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